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SIDS INFANTS DISEASE: Researchers Identify possible cause

Breakthrough: Researchers Identify Possible Cause Of Deadly SIDS Infants’ Disease


A sleep expert who lost her son to Sudden Infant Death Syndrome and spent the last 30 years looking for an answer for the inexplicable the disease may have made a breakthrough discovery helping to solve the puzzle.



My research started 29 years ago with the death of my precious son, Damien. Long and challenging work, but now we know that SIDS babies have low levels of the enzyme BChE. First time ever we can work with babies while still alive and prevent SIDS.


Now a study she has led has identified the first biochemical marker that could help detect babies more at risk of Sudden Infant Death Syndrome (SIDS) while they still live. “An apparently healthy baby going to sleep and not waking up is every parent’s nightmare and until now there was absolutely no way of knowing which infant would succumb. But that’s not the case anymore,” Harrington asserted.

“The study found BChE levels were significantly lower in babies who subsequently died of SIDS compared to living controls and other infant deaths,” Sydney Children’s Hospital Network reported, adding, “BChE plays a major role in the brain’s arousal pathway and researchers believe its deficiency likely indicates an arousal deficit, which reduces an infant’s ability to wake or respond to the external environment, causing vulnerability to SIDS”.
The study stated:

In recent years, the incidence of SIDS has been more than halved by public health campaigns however, despite this dramatic decline in incidence, SIDS remains the major cause of sudden and unexpected death in infants in western countries, contributing to almost 50% of all post-neonatal deaths.

The study explained that widespread current belief of the causes of SIDS rest on three simultaneous factors: “a vulnerable infant, a critical developmental period for homeostatic control and an exogenous stressor,” adding, “Despite intensive research over the past decades, identification of any specific vulnerability has remained elusive.”

Harrington stated, “Babies have a very powerful mechanism to let us know when they are not happy. Usually, if a baby is confronted with a life-threatening situation, such as difficulty breathing during sleep because they are on their tummies, they will arouse and cry out. What this research shows is that some babies don’t have this same robust arousal response.”

“This has long been thought to be the case, but up to now we didn’t know what was causing the lack of arousal,” she commented. “Now that we know that BChE is involved we can begin to change the outcome for these babies and make SIDS a thing of the past.”

“This discovery has opened up the possibility for intervention and finally gives answers to parents who have lost their children so tragically. These families can now live with the knowledge that this was not their fault,” she concluded.
Source:dailywire.com

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What is Postpartum Depression?Postpartum depression (PPD) is a complex mix of physical, emotional, and behavioral changes that happen in some women after giving birth. According to the DSM-5, a manual used to diagnose mental disorders, PPD is a form of major depression that begins within 4 weeks after delivery. The diagnosis of postpartum depression is based not only on the length of time between delivery and onset but on the severity of the depression.Postpartum depression is linked to chemical, social, and psychological changes that happen when having a baby. The term describes a range of physical and emotional changes that many new mothers experience. PPD can be treated with medication and counseling.The chemical changes involve a rapid drop in hormones after delivery. The actual link between this drop and depression is still not clear. But what is known is that the levels of estrogen and progesterone, the female reproductive hormones, increase tenfold during pregnancy. Then, they drop sharply after delivery. By 3 days after a woman gives birth, the levels of these hormones drop back to what they were before pregnancy.In addition to these chemical changes, the social and psychological changes of having a baby create an increased risk of depression.Most new mothers experience the “baby blues” after delivery. About 1 out of every 10 of these women will develop a more severe and longer-lasting depression after delivery. About 1 in 1,000 women develop a more serious condition called postpartum psychosis.Dads aren’t immune. Research shows that about 1 in 10 new fathers get depression during the year their child is born. *Postpartum Depression Signs and Symptoms*Symptoms of postpartum depression can be hard to detect. 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Some things that can raise the chances of postpartum depression include:•A history of depression prior to becoming pregnant, or during pregnancy•Age at time of pregnancy (the younger you are, the higher the chances)•Ambivalence about the pregnancyChildren (the more you have, the more likely you are to be depressed in a later pregnancy)•Family history of mood disorders•Going through an extremely stressful event, like a job loss or health crisis•Having a child with special needs or health problems•Having twins or triplets•Having a history of depression or premenstrual dysphoric disorder (PMDD)•Limited social support•Living alone•Marital conflictThere’s no one cause of postpartum depression, but these physical and emotional issues may contribute:*•Hormones*. The dramatic drop in estrogen and progesterone after you give birth may play a role. 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Usually you don’t need treatment from a health care provider for baby blues. Often, joining a support group of new moms or talking with other moms helps.•*Postpartum depression (PPD) *can happen a few days or even months after childbirth. PPD can happen after the birth of any child, not just the first child. You can have feelings similar to the baby blues — sadness, despair, anxiety, crankiness — but you feel them much more strongly. PPD often keeps you from doing the things you need to do every day. When your ability to function is affected, you need to see a health care provider, such as your OB/GYN or primary care doctor. This doctor can screen you for depression symptoms and come up with a treatment plan. If you don’t get treatment for PPD, symptoms can get worse. While PPD is a serious condition, it can be treated with medication and counseling.•*Postpartum psychosis* is a very serious mental illness that can affect new mothers. This illness can happen quickly, often within the first 3 months after childbirth. Women can lose touch with reality, having auditory hallucinations (hearing things that aren’t actually happening, like a person talking) and delusions (strongly believing things that are clearly irrational). Visual hallucinations (seeing things that aren’t there) are less common. Other symptoms include insomnia (not being able to sleep), feeling agitated and angry, pacing, restlessness, and strange feelings and behaviors. Women who have postpartum psychosis need treatment right away and almost always need medication. Sometimes women are put into the hospital because they are at risk for hurting themselves or someone else.*Postpartum Depression Treatment*Postpartum depression is treated differently, depending on the type of symptoms and how severe they are. Treatment options include anti-anxiety or antidepressant medications, psychotherapy, and participation in a support group for emotional support and education. For severe cases, an IV of a new medication called brexanolone (Zulresso) may be prescribed.In the case of postpartum psychosis, drugs used to treat psychosis are usually added. Hospital admission is also often necessary.If you are breastfeeding, don’t assume that you can’t take medication for depression, anxiety, or even psychosis. Talk to your doctor. Under a doctor’s supervision, many women take medication while breastfeeding. This is a decision to be made between you and your doctor.*Postpartum Depression Complications*Postpartum depression that isn’t treated can weaken your ability to bond with your baby, and affect the whole family:•*You*. Postpartum depression that’s not treated can last for months or longer, even turning into a chronic depressive disorder. Even with treatment, postpartum depression can make you more likely to have episodes of depression in the future.•*The baby’s father*. When a new mother has depression, the father may be more likely to have depression too.•*Children*. Children of mothers with postpartum depression are more likely to have problems with sleeping and eating, crying more than usual, and delays in language development.*Postpartum Depression Prevention*If you have a history of depression, tell your doctor as soon as you find out you’re pregnant, or if you’re planning to become pregnant.During pregnancy. Your doctor can monitor you for symptoms. You can manage mild depression symptoms with support groups, counseling, or other therapies. Your doctor may prescribe medications, even while you’re pregnant.After your baby is born. Your doctor may recommend an early postpartum checkup to look for symptoms of depression. The earlier you’re diagnosed, the earlier you can begin treatment. If you have a history of postpartum depression, your doctor may recommend treatment as soon as you have the baby.Managing after childbirthHere are some tips that can help you cope with bringing home a newborn:•Ask for help. Let others know how they can help you.•Be realistic about your expectations for yourself and baby.•Exercise , within the limits of any restrictions your doctor may place on your level of activity; take a walk, and get out of the house for a break.•Expect some good days and some bad days.•Follow a sensible diet; avoid alcohol and caffeine.•Foster the relationship with your partner — make time for each other.•Keep in touch with family and friends — don’t isolate yourself.•Limit visitors when you first go home.•Screen phone calls.•Sleep or rest when your baby sleeps.Source webmd.comWhat is Postpartum Depression?Postpartum depression (PPD) is a complex mix of physical, emotional, and behavioral changes that happen in some women after giving birth. According to the DSM-5, a manual used to diagnose mental disorders, PPD is a form of major depression that begins within 4 weeks after delivery. The diagnosis of postpartum depression is based not only on the length of time between delivery and onset but on the severity of the depression.Postpartum depression is linked to chemical, social, and psychological changes that happen when having a baby. The term describes a range of physical and emotional changes that many new mothers experience. PPD can be treated with medication and counseling.The chemical changes involve a rapid drop in hormones after delivery. The actual link between this drop and depression is still not clear. But what is known is that the levels of estrogen and progesterone, the female reproductive hormones, increase tenfold during pregnancy. Then, they drop sharply after delivery. By 3 days after a woman gives birth, the levels of these hormones drop back to what they were before pregnancy.In addition to these chemical changes, the social and psychological changes of having a baby create an increased risk of depression.Most new mothers experience the “baby blues” after delivery. About 1 out of every 10 of these women will develop a more severe and longer-lasting depression after delivery. About 1 in 1,000 women develop a more serious condition called postpartum psychosis.Dads aren’t immune. Research shows that about 1 in 10 new fathers get depression during the year their child is born. *Postpartum Depression Signs and Symptoms*Symptoms of postpartum depression can be hard to detect. Many women have these symptoms following childbirth:•Trouble sleeping •Appetite changes •Severe fatigue •Lower libido •Frequent mood changes With PPD, these come along with other symptoms of major depression, which aren’t typical after childbirth, and may include: •Being uninterested in your baby or feeling like you’re not bonding with them•Crying all the time, often for no reason•Depressed mood •Severe anger and crankiness•Loss of pleasure •Feelings of worthlessness, hopelessness, and helplessness •Thoughts of death or suicide •Thoughts of hurting someone else•Trouble concentrating or making decisionsSymptoms of obsessive compulsive disorder (OCD) that are new rarely occur in the postpartum period (about 1%-3% of women). The obsessions are usually related to concerns about the baby’s health or irrational fears of harming the baby. Panic disorder may also happen. You can have these conditions and depression at the same time.Untreated postpartum depression can be dangerous for new moms and their children. A new mom should seek professional help when:•Symptoms persist beyond 2 weeks•They can’t function normally•They can’t cope with everyday situations•They have thoughts of harming themselves or their baby•They’re feeling extremely anxious, scared, and panicked most of the day.*Postpartum Depression Causes and Risk Factors*If you have PPD, it’s not because you did anything wrong. Experts think it happens for many reasons, and those can be different for different people. Some things that can raise the chances of postpartum depression include:•A history of depression prior to becoming pregnant, or during pregnancy•Age at time of pregnancy (the younger you are, the higher the chances)•Ambivalence about the pregnancyChildren (the more you have, the more likely you are to be depressed in a later pregnancy)•Family history of mood disorders•Going through an extremely stressful event, like a job loss or health crisis•Having a child with special needs or health problems•Having twins or triplets•Having a history of depression or premenstrual dysphoric disorder (PMDD)•Limited social support•Living alone•Marital conflictThere’s no one cause of postpartum depression, but these physical and emotional issues may contribute:*•Hormones*. The dramatic drop in estrogen and progesterone after you give birth may play a role. Other hormones produced by your thyroid gland also may drop sharply and make you feel tired, sluggish and depressed.*•Lack of sleep.* When you’re sleep-deprived and overwhelmed, you may have trouble handling even minor problems. *•Anxiety*. You may be anxious about your ability to care for a newborn. *•Self Image.* You may feel less attractive, struggle with your sense of identity, or feel that you’ve lost control over your life. _Any of these issues can contribute to postpartum depression._*Types of postpartum depression*There are three terms used to describe the mood changes women can have after giving birth:•The “baby blues”happen to as many as 70% of women in the days right after childbirth. You may have sudden mood swings, such as feeling very happy and then feeling very sad. You may cry for no reason and can feel impatient, cranky, restless, anxious, lonely, and sad. The baby blues may last only a few hours or as long as 1 to 2 weeks after delivery. Usually you don’t need treatment from a health care provider for baby blues. Often, joining a support group of new moms or talking with other moms helps.•*Postpartum depression (PPD) *can happen a few days or even months after childbirth. PPD can happen after the birth of any child, not just the first child. You can have feelings similar to the baby blues — sadness, despair, anxiety, crankiness — but you feel them much more strongly. PPD often keeps you from doing the things you need to do every day. When your ability to function is affected, you need to see a health care provider, such as your OB/GYN or primary care doctor. This doctor can screen you for depression symptoms and come up with a treatment plan. If you don’t get treatment for PPD, symptoms can get worse. While PPD is a serious condition, it can be treated with medication and counseling.•*Postpartum psychosis* is a very serious mental illness that can affect new mothers. This illness can happen quickly, often within the first 3 months after childbirth. Women can lose touch with reality, having auditory hallucinations (hearing things that aren’t actually happening, like a person talking) and delusions (strongly believing things that are clearly irrational). Visual hallucinations (seeing things that aren’t there) are less common. Other symptoms include insomnia (not being able to sleep), feeling agitated and angry, pacing, restlessness, and strange feelings and behaviors. Women who have postpartum psychosis need treatment right away and almost always need medication. Sometimes women are put into the hospital because they are at risk for hurting themselves or someone else.*Postpartum Depression Treatment*Postpartum depression is treated differently, depending on the type of symptoms and how severe they are. Treatment options include anti-anxiety or antidepressant medications, psychotherapy, and participation in a support group for emotional support and education. For severe cases, an IV of a new medication called brexanolone (Zulresso) may be prescribed.In the case of postpartum psychosis, drugs used to treat psychosis are usually added. Hospital admission is also often necessary.If you are breastfeeding, don’t assume that you can’t take medication for depression, anxiety, or even psychosis. Talk to your doctor. Under a doctor’s supervision, many women take medication while breastfeeding. This is a decision to be made between you and your doctor.*Postpartum Depression Complications*Postpartum depression that isn’t treated can weaken your ability to bond with your baby, and affect the whole family:•*You*. Postpartum depression that’s not treated can last for months or longer, even turning into a chronic depressive disorder. Even with treatment, postpartum depression can make you more likely to have episodes of depression in the future.•*The baby’s father*. When a new mother has depression, the father may be more likely to have depression too.•*Children*. Children of mothers with postpartum depression are more likely to have problems with sleeping and eating, crying more than usual, and delays in language development.*Postpartum Depression Prevention*If you have a history of depression, tell your doctor as soon as you find out you’re pregnant, or if you’re planning to become pregnant.During pregnancy. Your doctor can monitor you for symptoms. You can manage mild depression symptoms with support groups, counseling, or other therapies. Your doctor may prescribe medications, even while you’re pregnant.After your baby is born. Your doctor may recommend an early postpartum checkup to look for symptoms of depression. The earlier you’re diagnosed, the earlier you can begin treatment. If you have a history of postpartum depression, your doctor may recommend treatment as soon as you have the baby.Managing after childbirthHere are some tips that can help you cope with bringing home a newborn:•Ask for help. Let others know how they can help you.•Be realistic about your expectations for yourself and baby.•Exercise , within the limits of any restrictions your doctor may place on your level of activity; take a walk, and get out of the house for a break.•Expect some good days and some bad days.•Follow a sensible diet; avoid alcohol and caffeine.•Foster the relationship with your partner — make time for each other.•Keep in touch with family and friends — don’t isolate yourself.•Limit visitors when you first go home.•Screen phone calls.•Sleep or rest when your baby sleeps.Source webmd.com

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